Wash. U. Docs Provide Another Excuse to Keep Drinking Red Wine

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The elixer of life!
Red wine has been firmly established as the wonder drug of our time. It prevents blindness, skin cancer, diabetes, heart disease and tooth decay! It fights radiation and food poisoning! It makes you thin and young and lovely and French! Whoops, not French, sorry, we got a little carried away there. But it does cure impotence.

For years scientists have been trying to figure out red wine's secret wonder ingredient. (That's part of being a scientist. You can't ever just appreciate a good thing. You have to figure out what makes it work.) A few years ago, scientists thought they'd found it: a compound called resveratrol.

But now a team of researchers at Wash. U. has put the kibosh on that. And thank goodness, because the National Institute of Health actually had this crazy idea that people could stop drinking wine and just take resveratrol tablets instead.

"Few studies have evaluated the effects of resveratrol in people," said Dr. Samuel Klein, the lead investigator of the study. "Those studies were conducted on people with diabetes, older adults with impaired glucose tolerance or obese people who had more metabolic problems."

So instead Klein and his team decided to evaluate a group that was comprised of neither mice nor sick old people: 29 non-obese, non-diabetic, post-menopausal women. Not a particularly large or diverse sample, it's true. But it was a start.

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As the scientist in the article stated, the fault here is with the study itself, not the resveratrol used in the study.  The dosage used in this study was rediculously low, compared to all earlier studies.  In the case of the successful Albert Einstein Medical School study and the more recent Florida Pharmacology School study the dosages were approximately 10 to 20 times this amount.  This dosage is consistent with the supplements used in those trials, specifically biotivia transmax and bioforte, which are readily available without a prescription. Using a dosage of only 75mg was tantmount to giving a heart attack victim one aspirin. In all previous studies on actual type 2 diabetic patients or those suffering impaired glucose tolerance, a sign of impending diabetes, resveratrol was extremely effective in improving glucose tolerance, enhancing metobolic function and blocking the onset of diabetes.   As a cell biologist who has been involved in several human clinical trials of transmax and bioforte resveratrol against diabetes, I can only imagine that this study was designed by a pharmaceutical company to fail intentionally.  The pharmas are clearly aware of the potential of resveratrol to cut into their sales of Metformin, a multi-billion dollar earner for the drug companies, and are on a campaign to discredit the compound.  As a researcher I question why the clicinicans in this study would select as subjects women who have no issues with glucose tolerance, who were nonobese, and who did not exhibit signs of diabetes.  This is equivalent to testing a compound designed to treat cancer on a group of subjects none of whom has cancer. Again, we see a troubling signal of possible pharma involvement.

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